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Bioreactor Drive Systems

Bioreactor Drive Systems

Each engineered tissue requires a unique set of culture growth conditions to optimize outcomes. Our customers often spend decades perfecting the tissue culture “recipe” of cells/biomaterials/culture medium, bioreactor chamber, and mechanical loading and fluid flow conditions. Recognizing these efforts and the drawbacks of switching to a different bioreactor chamber, we have developed bioreactor drive systems that connect to your existing bioreactor chamber.

 

You can now leverage your current bioreactor chamber design and prior data, while taking advantage of a robust, fully-automated and scalable bioreactor drive system. Each oscillatory flow bioreactor drive system can have up to 4 pump cartridges installed that can connect to 4 customer-provided bioreactor chambers. Multiple drive systems can be controlled by a single laptop computer, and each drive system can have a different stimulation waveform profile.  

 

  • Moving magnet and flexure assembly linear motor with infinite fatigue life
  • Independent flow loops
  • Smooth hardware and software transducer integration
  • Standard and custom stimulation waveforms
  • Conditional branching for automated stimulation changes based on tissue maturation milestones
  • System alerts via text/email messaging
  • 21 CFR Part 11 compliant software with user level permissions to protect electronic records and provide audit trail documentation
  • GMP facility compliant design (no lubricants, non-reactive, additive, or absorptive surfaces) and documentation


Bioreactor drive systems for axial loading (tension, compression) that can connect to your bioreactor chambers are also available. Contact our engineers to discuss your manufacturing process and bioreactor system requirements.




Oscillatory Flow Bioreactor Drive System Specifications

Pump Cartridges - Flow Loops

1, 2, 3 or 4

Pump Cartridge Volumetric Output per mm of Displacement

0.5 ml/mm for ± 6.0mm displacement

Pump Cartridge Design

Double Integrated Checkvalve 

(Checkvalves are removable)

Displacement Transducer Type

LVDT Non-Contacting

Pressure Transducer Calibrated Output Range

+/-350 mmHg

Laptop Operating System

Windows 10

BDS Linear Drive Output Frequency Range

0 to 10Hz

BDS Linear Drive Waveform Types

Sine, Triangle, Square, Ramp and Block 

BDS Controller Output Channels - Two (2)

·  Drive signal to the Linear Motor

·  Digital Output to Motor Amp

BDS Controller +/-10V Analog Input Channels - Eight (8)

·  Displacement

·  Press1

·  Press2

·  Press3

·  Press4

·  Laser

·  Aux1 

·  Aux2 

BDS Input Voltage

100-240VAC

BDS Input Power

60W

 


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